yybP [2018-05-30 17:49:28]

membrane protein, may be involved in manganese detoxification

Locus: BSU40560

Isoelectric point: 4.24

Molecular weight: 15.83 kDa

Protein length: 148 aa

Gene length: 444 bp

Function: unknown

Product: unknown

Essential: no

Synonyms

Genomic Context

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Categories containing this gene/protein

• Lifestyles → Sporulation → Sporulation proteins → Newly identified sporulation proteins (based on transcription profiling)
• Groups of genes → Membrane proteins

Gene

Coordinates: 4,169,166 → 4,169,612

The protein

Structure

• 3LLL (from the mouse, 28% identity) PubMed

Localization

• cell membrane (according to Swiss-Prot)

Expression and Regulation

Operons

• Genes: yybP
  Description: PubMed

  Regulatory mechanism

  • yybP-ykoY motif: antitermination, in the presence of the ligand Mn²⁺ PubMed, in yybP-ykoY motif

  Regulation

  • induced in the presence of Mn²⁺ (yybP-ykoY motif) PubMed
  • the RNA switch RNA is degraded by RNase Y PubMed

Biological materials

Mutant

• MGNA-B838 (yybP::erm), available at the NBRP B. subtilis, Japan
• BKE40560 (ΔyybP::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATCTTCAGCCCCCTCATCG, downstream forward: _UP4_TAAGAAAAAGCATCCCGACG
• BKK40560 (ΔyybP::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATCTTCAGCCCCCTCATCG, downstream forward: _UP4_TAAGAAAAAGCATCCCGACG

References

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